Several neurologic disorders including multiple sclerosis, spinal cord injury, neurotrauma and HIV encephalomyelopathy are associated with loss or dysfunction of myelin, the protective covering of neurons. A group of scientists at McGill University reported earlier that RNS60 supports the survival and differentiation of myelin producing oligodendrocytes. Here, researchers from Rush University showed that RNS60 promotes the expression of genes that synthesize the myelin sheath. These results demonstrated a novel property of RNS60, which may be of therapeutic benefit for demyelinating disorders.
Link to the paper: Upregulation of Myelin Gene Expression by a Physically-Modified Saline via Phosphatidylinositol 3-Kinase-Mediated Activation of CREB: Implications for Multiple Sclerosis | SpringerLink