Researchers at the Mario Negri Institute for Pharmacological Research in Milan, Italy conducted a study to test the therapeutic effect of RNS60 in a widely used mouse model of ALS. In this model, RNS60 treatment starting after disease onset demonstrated significant therapeutic efficacy. RNS60 protected spinal motor neurons and neuromuscular junctions and slowed the disease progression. The data, published in the Journal of Neuroinflammation, strongly support further development of RNS60 in ALS.

Link to the paper: RNS60 exerts therapeutic effects in the SOD1 ALS mouse model through protective glia and peripheral nerve rescue | Journal of Neuroinflammation | Full Text (biomedcentral.com)